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Research

Fetal signatures in the 3D genome of iPSC-derived neurons and their implications for disease modeling

  • Diana Zagirova
  • Anna Kononkova
  • Kirill Morozov
  • Maria Molodova
  • Nikita Vaulin
  • Anastasiia Dudkovskaia Polina Dozorova Olga Efimova Anna Tvorogova Kirill Ulianov Philipp Khaitovich
  • ... [+6 authors] ...,
  • Sergey Razin
  • Maria Lagarkova
  • Sergey Ulianov
  • Ekaterina Khrameeva
  • First Published August 3, 2026
Research

MEIS1 in conferring sleep abnormalities and impaired cerebellar development" > Cross-species variant-to-function analyses implicate MEIS1 in conferring sleep abnormalities and impaired cerebellar development

  • Amber Zimmerman
  • Erika Almeraya Del Valle
  • Matthew Pahl
  • Fusun Doldur-Balli
  • Brendan Keenan
  • Patrick Liu Zoe Shetty Trisha Tsundupalli Justin Palermo Anitra Krishnan James Pippin Andrew Wells Olivia Veatch Alessandra Chesi
  • ... [+9 authors] ...,
  • Philip Gehrman
  • Alex Keene
  • Allan Pack
  • Struan F.A. Grant
  • First Published July 30, 2026
Research

Moderated designs can balance between batch-effect mitigation and cell loss due to hashtag-assisted pooling in single-cell experiments

  • Budha Chatterjee
  • Katrina Gorga
  • Carly Blair
  • Yuko Ohta
  • Michelle Radov
  • Elizabeth M Hill
  • Christopher T Boughter
  • Martin Meier-Schellersheim
  • Nevil J. Singh
  • First Published July 30, 2026
Method

Fast and memory efficient partial order alignment with minipoa

  • Haodong Liu
  • Pinglu Zhang
  • Yanming Wei
  • Qinzhong Tian
  • Yixiao Zhai
  • Quan Zou
  • Mengting Niu
  • First Published July 24, 2026
Method

Knowledge-driven interpretable neural networks for mechanistic insight

  • Yan Ke
  • Tianwei Yu
  • First Published July 24, 2026
In memoriam

Jim Watson (1928–2025): a genomics visionary

  • Aravinda Chakravarti
  • Evan E. Eichler
  • Anne C. Ferguson-Smith
  • Richard A. Gibbs
  • Eric D. Green
  • John R. Inglis
  • Kateryna D. Makova
  • Richard M. Myers
  • Hillary E. Sussman
  • First Published July 23, 2026
Method

Multisource omic alignment and biological feature discovery with Performer encoder and triplet networks

  • Zihuan Du
  • Xiaoyu Zhang
  • Qiang Zhang
  • Jing Li
  • Zhijie Cao
  • Ge Gao
  • Tao Lin
  • Dong Wang
  • Shuai Gao
  • First Published July 22, 2026
Method

Mosaic integration of spatial multiomic data based on hierarchical graph contrastive learning with SpatialMOSI

  • Peimeng Zhen
  • Han Shu
  • Bingtao Wang
  • Yongtian Wang
  • Jialu Hu
  • Jiajie Peng
  • Xuequn Shang
  • Tao Wang
  • Jing Chen
  • First Published July 22, 2026
Research

Identification of genomic features that uniquely impact estrogen receptor alpha binding and its effects on gene expression in endometrial cancer

  • Alexandra Richey
  • Noel Kitchen
  • Craig M Rush
  • Jeffery M Vahrenkamp
  • Hosiana Abewe
  • Kyle S Osborne
  • ... [+1 authors] ...,
  • Alex J Bott
  • Brian K Dalley
  • Jared Rutter
  • Jason Gertz
  • First Published July 17, 2026
Research

Methylation variability and LINE-1 transcriptional activation in multiple myeloma

  • Qianhui Wan
  • Amy Leung
  • Mahek Vinod Bhandari
  • Hiroyuki Kato
  • Joo Y Song
  • Dustin Schones
  • First Published July 17, 2026
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