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Research: The landscape of genomic imprinting across diverse adult human tissues
- Yael Baran,
- Meena Subramaniam,
- Anne Biton,
- Taru Tukiainen,
- Emily K. Tsang,
- Manuel A. Rivas,
- Matti Pirinen,
- Maria Gutierrez-Arcelus,
- Kevin S. Smith,
- Kim R. Kukurba,
- Rui Zhang,
- Celeste Eng,
- Dara G. Torgerson,
- Cydney Urbanek,
- the GTEx Consortium,
- Jin Billy Li,
- Jose R. Rodriguez-Santana,
- Esteban G. Burchard,
- Max A. Seibold,
- Daniel G. MacArthur,
- Stephen B. Montgomery,
- Noah A. Zaitlen,
- and Tuuli Lappalainen
Genome Res. July 2015 25: 927-936; Published in Advance May 7, 2015, doi:10.1101/gr.192278.115
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Research: Genome-scale mutational signatures of aflatoxin in cells, mice, and human tumors
- Mi Ni Huang,
- Willie Yu,
- Wei Wei Teoh,
- Maude Ardin,
- Apinya Jusakul,
- Alvin Wei Tian Ng,
- Arnoud Boot,
- Behnoush Abedi-Ardekani,
- Stephanie Villar,
- Swe Swe Myint,
- Rashidah Othman,
- Song Ling Poon,
- Adriana Heguy,
- Magali Olivier,
- Monica Hollstein,
- Patrick Tan,
- Bin Tean Teh,
- Kanaga Sabapathy,
- Jiri Zavadil,
- and Steven G. Rozen
Genome Res. September 2017 27: 1475-1486; Published in Advance July 24, 2017, doi:10.1101/gr.220038.116
...xenosensors (-endosulfan and 2, 3, 7, 8 tetrachlorodibenzo-p-dioxin) interact in a mixture and downregulate multiple genes involved in human hepatocyte lipid and glucose. Biochimie 116: 7991. Bailey EA, Iyer RS, Stone MP, Harris TM, Essigmann JM. 1996. Mutational properties of the primary aflatoxin B1-DNA ...
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Research: A-type lamins bind both hetero- and euchromatin, the latter being regulated by lamina-associated polypeptide 2 alpha
- Kevin Gesson,
- Philipp Rescheneder,
- Michael P. Skoruppa,
- Arndt von Haeseler,
- Thomas Dechat,
- and Roland Foisner
Genome Res. April 2016 26: 462-473; Published in Advance January 21, 2016, doi:10.1101/gr.196220.115
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Method: Multikernel linear mixed models for complex phenotype prediction
- Omer Weissbrod,
- Dan Geiger,
- and Saharon Rosset
Genome Res. July 2016 26: 969-979; Published in Advance June 14, 2016, doi:10.1101/gr.201996.115
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Research: Global deceleration of gene evolution following recent genome hybridizations in fungi
- Sira Sriswasdi,
- Masako Takashima,
- Ri-ichiroh Manabe,
- Moriya Ohkuma,
- Takashi Sugita,
- and Wataru Iwasaki
Genome Res. August 2016 26: 1081-1090; Published in Advance July 20, 2016, doi:10.1101/gr.205948.116
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Research: Genomes of Ellobius species provide insight into the evolutionary dynamics of mammalian sex chromosomes
- Eskeatnaf Mulugeta,
- Evelyne Wassenaar,
- Esther Sleddens-Linkels,
- Wilfred F.J. van IJcken,
- Edith Heard,
- J. Anton Grootegoed,
- Walter Just,
- Joost Gribnau,
- and Willy M. Baarends
Genome Res. September 2016 26: 1202-1210; Published in Advance August 10, 2016, doi:10.1101/gr.201665.115
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Research: Replication timing is regulated by the number of MCMs loaded at origins
- Shankar P. Das,
- Tyler Borrman,
- Victor W.T. Liu,
- Scott C.-H. Yang,
- John Bechhoefer,
- and Nicholas Rhind
Genome Res. December 2015 25: 1886-1892; Published in Advance September 10, 2015, doi:10.1101/gr.195305.115
...) grant to J.B. References Alvino GM, Collingwood D, Murphy JM, Delrow J, Brewer BJ, Raghuraman MK. 2007. Replication in hydroxyurea: Its amatter of time.Mol Cell Biol 27: 63966406. Bechhoefer J, Rhind N. 2012. Replication timing and its emergence from stochastic processes. Trends Genet 28: 374 ...
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Method: Modeling Niemann–Pick disease type C in a human haploid cell line allows for patient variant characterization and clinical interpretation
- Steven Erwood,
- Reid A. Brewer,
- Teija M.I. Bily,
- Eleonora Maino,
- Liangchi Zhou,
- Ronald D. Cohn,
- and Evgueni A. Ivakine
Genome Res. December 2019 29: 2010-2019; Published in Advance November 21, 2019, doi:10.1101/gr.250720.119
..., Obernosterer G, Mulherkar N, Kuehne AI, Kranzusch PJ, Griffin AM, Ruthel G, et al. 2011. Ebola virus entry requires the cholesterol transporter NiemannPick C1. Nature 477: 340343. doi:10.1038/nature10348 Cho SW, Kim S, Kim JM, Kim JS. 2013. Targeted engineering in human cells with the Cas9 RNA ...
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Method: Identifying gene function and module connections by the integration of multispecies expression compendia
- Hao Li,
- Daria Rukina,
- Fabrice P.A. David,
- Terytty Yang Li,
- Chang-Myung Oh,
- Arwen W. Gao,
- Elena Katsyuba,
- Maroun Bou Sleiman,
- Andrea Komljenovic,
- Qingyao Huang,
- Robert W. Williams,
- Marc Robinson-Rechavi,
- Kristina Schoonjans,
- Stephan Morgenthaler,
- and Johan Auwerx
Genome Res. December 2019 29: 2034-2045; Published in Advance November 21, 2019, doi:10.1101/gr.251983.119
...JG, Root DE, Mootha VK. 2016. A -wide CRISPR death screen identifies genes essential for oxidative phosphorylation. Cell Metab 24: 875885. doi:10.1016/j.cmet.2016.08.017 Ashburner M, Ball CA, Blake JA, Botstein D, Butler H, Cherry JM, Davis AP, Dolinski K, Dwight SS, Eppig JT, et al. 2000. Gene ...
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Research: High-throughput functional analysis of lncRNA core promoters elucidates rules governing tissue specificity
- Kaia Mattioli,
- Pieter-Jan Volders,
- Chiara Gerhardinger,
- James C. Lee,
- Philipp G. Maass,
- Marta Melé,
- and John L. Rinn
Genome Res. March 2019 29: 344-355; Published in Advance January 25, 2019, doi:10.1101/gr.242222.118
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