A Protein Interaction Framework for Human mRNA Degradation
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Summary tables of all interactions
The following links are to Word documents.
Protein interactions detected by Y2H matrix experiments.
Protein interactions detected by Y2H library screens.
Results for each Y2H screen
For each prey, the following information is shown (when available):
| Ists | Number of colonies of each prey isolated |
| UGCluster | The Unigene Cluster ID for the prey |
| Aliases | Other names for this gene |
| UGRepAcc | A representitive accession from NCBI |
| SumFunc | Summary function annotations |
| GO | Gene Ontology annotations |
| ExtAnnot | Other annotations |
| SPFunction | Summary function from Swissprot |
| SPLocal | Subcellular localization from Swissprot. Secreted and mitochondrial proteins are shaded. |
Exosome complex
Rrp41
Rrp42/Kiaa0116 no interactions
Rrp46
PM/Scl-75/Rrp45 no interactions
Mtr3
Oip2
Rrp4
Rrp40
Csl4
PM/Scl-100/Rrp6
PM/Scl-100/Rrp6 exonuclease [1-456]
PM/Scl-100/Rrp6 HRDC [503-583]
PM/Scl-100/Rrp6 [584-860]
Kiaa0052 self-active bait
Mpp6
Rrp44 no interactions
Rrp44 PinC [1-182]
Rrp44 PinC+CSP [1-387] no interactions
Rrp44 RNase II+RNB [388-958] no interactions
Ski2 self-active bait
Ski2 helicase [1-708] self-active bait
Ski2 [709-1246]
Lsm proteins
Lsm1
Lsm2
Lsm3
Lsm4
Lsm5
Lsm6
Lsm7
Lsm8
Decapping factors
Dcp2
Dcp2B (without exons 8 and 9)
Dcp1A self-active bait
Dcp1B self-active bait
DcpS no interactions
5'>3' exonulceases
Xrn1/Sep1 Exonuclease [1-300]
Xrn1/Sep1 [578-1470] no interactions
Xrn1/Sep1 RBD [1440-1707]
Xrn2/Rat1
Xrn2/Rat1 Exonuclease [1-280]
Dom3
5'>Poly(A) ribonuclease
PARN
5'>AU-rich binding proteins
TTP self-active bait
Auf1/hnRNPD (variant 3)
HuR no interactions
5'>Nonsense-mediated decay factors
Upf1 [1-415] no interactions
Upf1 helicase [416-701] no interactions
Upf1 [702-1119]
Upf2 [1-167] no interactions
Upf2 MIF4G1+2 [166-758] no interactions
Upf2 [757-1272]
Upf3A (variant2)
Upf3B
5'>Other
Znf408
For enquiries please email blehner{at}hgmp.mrc.ac.uk
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This Article
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doi: 10.1101/gr.2122004 Genome Res. July 2004 vol. 14 no. 7 1315-1323
