Shuffling of Genes Within Low-Copy Repeats on 22q11 (LCR22) by Alu-Mediated Recombination Events During Evolution
D5 1 ttatctccagcataatgact gttttgatccttgtaaaaaaggtgattttt
D5c 1 ---------- ---------- ---------- ---------- ----------
D5e 1 tcatctccagcataatgact cttttgatccttgtaaaaaaggtgattttt
AluSx 1 ---------- ---------- ---------- ---------- ----------
D5 51 GGCTGGGTGTGGTGGCTCACACCTGTGATCCCAGCACTTTGGGAGGCTGA
D5c 1 ---------- ---------- ---------- ---------- ----------
D5e 51 GGCTGGGTGTGGTGGCTCACACCTGTAATCCCAGCACTTTGGGAGGCTGA
AluSx 1 GGCCGGGCGC GGTGGCTCAC GCCTGTAATCCCAGCACTTTGGGAGGCCGA
D5 101 GGCGGGTGGATCATTTAAGGTCAGGAGTTGGAGACCAGCCTGGGCAACAT
D5c 1 ---------- ---------- ---------- ---------ctttcactgca
D5e 101 GGGGGGTGGC TCACTTGAAGTCAGGAGTTGGAGACCAGCCTGGGCAACAT
AluSx 51 GGCGGGCGGATCACCTGAGGTCAGGAGTTC GAGACCAGCCTGGCCAACAT
D5 151 GGTGAAACCACGTCTCTACTAAAAATACAAAAATTAGCTGGGCATGGTAG
D5c 12 tgcacatctc atccaaatac caccacatgg tggatgctTGGGCATGGTAG
D5e 151 GGTGAAACCACGTtctcctg ggtgtccagg tggtccaaga ccccatgact
AluSx 101 GGTGAAACCC CGTCTCTACTAAAAATACAAAAATTAGCCGGGCGTGGTGG
D5 201 CGGGTGCCTGTAATCCCAGCTACTTGGGAGGCTGAGACAGGAGAATCACT
D5c 62 CGGGTGCCTGTAATCCCAGCTACTTGGGAGGCTGAGACAGGAGAATCACT
D5e 201 atatcatgac aggaaagag- ---------- ---------- ----------
AluSx 151 CGCGCGCCTGTAATCCCAGCTACTCGGGAGGCTGAGGCAGGAGAATCGCT
D5 251 TGAACCCAGGAGGCAAAGGTTGCAGTAAGCCAAGATTGCACCACTGCACT
D5c 112 TGAACCCAGGAGGCAAAGGTTGCAGTAAGCCAAGATTGCACCACTGCACT
D5e 220 ---------- ---------- ---------- ---------- ----------
AluSx 201 TGAACCCGGGAGGCGGAGGTTGCAGTGAGCCGAGATCGCG CCACTGCACT
D5 301 CCAGCCTGGGTGACAGAGCAAGACTTGGTCTCAGG---aaaaaaaaaaaa
D5c 162 CCAGCCTGGGTGACAGAGCAAGACTTGGTCTCAaaaaaaaaaaaaaaaaa
D5e 220 ---------- ---------- ---------- ---------- ----------
AluSx 251 CCAGCCTGGG CGACAGAGCG AGACTCCGTCTCA------- ----------
D5 348 agaaagaaagaaaagtttatatttttgttctaatggttatcttaatatct
D5c 212 aaaaagaaagaaaagtttatatttttgttctaatggttatcttaatatct
D5e 220 ---------- ---------- ---------- ---------- ----------
AluSx 284 ---------- ---------- ---------- ---------- ----------
D5 398 tcattctataattat
D5c 262 tcattctataat---
D5e 220 ---------- -----
AluSx 284 ---------- -----
