Shuffling of Genes Within Low-Copy Repeats on 22q11 (LCR22) by Alu-Mediated Recombination Events During Evolution
D4 1 ccaccatgcc cagcataact atttttaatg aagtagactt taagaagaaa
D4b 1 catgggccgg aagggcggtc aggatcgggg gacgatccta ataatactac
AluSp 1 ---------- ---------- ---------- ---------- ----------
D4 51 agtattatta gagataagag acacatcatg gaaaagaagaaattactagg
D4b 51 taatctaata atacttttct tcttaaagtc tacttcattaaaaatagtta
AluSp 1 ---------- ---------- ---------- ---------- ----------
D4 101 AGACGGGTGC AGTAGTTCATGCCTGTAATCCCAGCACTTTG--GGAGGCC
D4b 101 TGCTGGGCAT GGTGGCTCATGACTGTAATC TCGGCACTTTGTTGGAGGTC
AluSp 1 GGCCGGGCGCGGTGGCTCAC GCCTGTAATCCCAGCACTTTG--GGAGGCC
D4 149 AAAGCGGGCA GATCACCTGAGGTCGGGAGTTTGAGACCAGCCTGACCCAC
D4b 151 GAGGTGGGTGGATCACTGAAGCCCAGGAGTTCAAGACCAGCCTGACGAAC
AluSp 49 GAGGCGGGCGGATCACCTGAGGTCGGGAGTTCGAGACCAGCCTGACCAAC
D4 199 ATGGAGAAACCCTGTCTCTACCAAAAATACAAAA-TTAGCCAGGTGTGGT
D4b 201 ATGGAGAAGCCCTGTCTCTACTAAAAATACAAAAATTAGCCAAGCATGGT
AluSp 99 ATGGAGAAACCCCGTCTCTACTAAAAATACAAAAATTAGCCGGGCGTGGT
D4 248 GGCGCATGCCTGTAATCCCAGCTACTCAGGAGGCTGAGGCAGGAGAATCG
D4b 251 GGCACATGCCTGTAATCCCAGCTACTCAGGAGGCTGAGGG AGGAGAATTG
AluSp 149 GGCGCATGCCTGTAATCCCAGCTACTCGGGAGGCTGAGGCAGGAGAATCG
D4 298 CTTGAACCCAGGAGGTGGAGGTTGCGGTGAGCCAAGATCGTGCTATTGTA
D4b 301 CTTGGACCCAGGAAGTGGAGGTTGCGGTGAGCTGAGATTGTGCCATTGCA
AluSp 199 CTTGAACCCG GGAGGCGGAGGTTGCGGTGAGCCGAGATCG CGCCATTGCA
D4 348 CTCCAGCCTG TGCAACAAGA ACAAAACTCC ATCTCAaaaaaaaaaaaaaa
D4b 351 TTCCAGCCTGGGCAACAAGA CCAAAACTCT GTCTCAaaaaaacaaaaaaa
AluSp 249 CTCCAGCCTGGGCAACAAGA GCGAAACTCCGTCTCA---- ----------
D4 398 aaaaaacacg aggttactagctagtttcagtattacttaacatccaggaa
D4b 401 aaaaga---- -agttactagctagtttcagtaattcttaacatccaggaa
AluSp 285 ---------- ---------- ---------- ---------- ----------
D4 448 actggatata gaagtttttt tagagaaactaaacc
D4b 446 actggatgtg aaagc-tttt cagagaaactaaacc
AluSp 285 ---------- ---------- ---------- -----
