Shuffling of Genes Within Low-Copy Repeats on 22q11 (LCR22) by Alu-Mediated Recombination Events During Evolution
A4 1 gcaacaaagcaagactccatctctaaaaataaaattaaat -taaaaaaaa
A4a1 1 gcaacaaagcaagactccatctctaaaaataaaataaaattaaaaaaaaa
A4a2 1 gcaacaaagcaagactccatctctaaaaataaaataaaatttaaaaaaaa
AluSc 1 ---------- ---------- ---------- ---------- ----------
A4 50 gatcttcgctgtaaaagaggtatgctcaaatgcaataaaagcatataaga
A4a1 51 gatcttcgctgtaaaagaggtacgctcaaatgcaataaaagcatataaga
A4a2 51 gatcttcgctgtaaaagaggtacgctcaaatgcaataaaagcatataaga
AluSc 1 ---------- ---------- ---------- ---------- ----------
A4 100 aGGCCAGGTGTGGTGGCTCATGCCTGTAATCCCAGCACTTTGGGAGGCTG
A4a1 101 aGGCCGGGTGTGGTGGCTCATGCCTGTAATCCCAGCACTTTGGGAGGCCG
A4a2 101 aGGCCGGGTGTGGTGGCTCATGCCTGTAATCCCAGCACTTTGGGAGGCCG
AluSc 1 -GGCCGGGCG CGGTGGCTCA CGCCTGTAATCCCAGCACTTTGGGAGGCCG
A4 150 AGGCAGGTGGATCATGAGGTCAAGAGACTGAGACCATCCTGGCCAACATG
A4a1 151 AGACGGGCGGATCACGAGGTCAGGAGATTGAGACTATCCTGGCTAACGCG
A4a2 151 AGACGGGCGGATCACGAGGTCAGGAGATTGAGACTATCCTGGCTAACGCG
AluSc 50 AGGCGGGCGGATCACGAGGTCAAGAGATCGAGACCATCCTGGCCAACATG
A4 200 GTGAAACACC GTCTCTACTAAAAATACAAAAAACAATCAGCTGGGCGTGG
A4a1 201 GTGAAACCCCATCTCCTCTAAAAGTACAAAAAA--ATTAGCTGGGCTAGG
A4a2 201 GTGAAACCCCATCTCCTCTAAAAGTACAAAAAA--ATTAGCTGGGCTAGG
AluSc 100 GTGAAACCCC GTCTCTACTAAAAATAC--AAAA--ATTAGCTGGGCGTGG
A4 250 TGGCACACACCTGTAGTCCCAGCTACTCAGGAGGCTGAGGCAGGAGAATC
A4a1 249 TGGCAGGCGCCTGTAG---- ---------- ---------- ----------
A4a2 249 TGGCAGGCGCCTGTAG---- ---------- ---------- ----------
AluSc 146 TGGCGCGCGCCTGTAGTCCCAGCTACTCGGGAGGCTGAGGCAGGAGAATC
A4 300 GCTTGAACCT GGGAGGAGGAGCCAAGTGTA GTAGCCAAGATTGTGCCACT
A4a1 265 ---------- ---------- ---------- ---------- ----------
A4a2 265 ---------- ---------- ---------- ---------- ----------
AluSc 196 GCTTGAACCC GGGAGGCGGAGGTTGCAGTG --AGCCGAGATCGCGCCACT
A4 350 ACACTCCAGCCCGGCAACAGAGCGAGACTCCGTCAAA
A4a1 265 ---------- ---------- ---------- -------
A4a2 265 ---------- ---------- ---------- -------
AluSc 244 GCACTCCAGCCTGGCGACAGAGCGAGACTCCGTCTCA
