Shuffling of Genes Within Low-Copy Repeats on 22q11 (LCR22) by Alu-Mediated Recombination Events During Evolution
A2 1 catctcaaaa caaacaaaca aacaaacaaa aaaacagtgt gatGGCCAGG
A2b 1 -ctagtgagc acactgtata cgacatcgct aatgaggatg ctaTATATGA
AluJo 1 ---------- ---------- ---------- ---------- ---GGCCGGG
A2 51 CGCAGT-GCTCATGCCTATAATCCAAGCACTTTGGGAGGC TGAAATGGAT
A2b 50 CATCGCTGAT GAGGACGTTG TACACGACAT CACTAATGAG GACACCATAC
AluJo 8 CGCGGTGGCTCACGCCTGTAATCCCAGCACTTTGGGAGGC CGAGGCGGGA
A2 100 GGATGGCTTGAGCCCAGTAGTTTGAGACAAGCCT-GGCAACATAGCGAGA
A2b 100 AGATGGCTTGAGCCCAGTAGTTTGAGACAAGCCT-GGCAACACAGCGAGA
AluJo 58 GGATTGCTTGAGCCCAGGAGTTCGAGACCAGCCTGGGCAACATAGCGAGA
A2 149 CCTCATCTCTACAAACATCTTT--AAAATATGCCAGGCATGGTGGTGCAT
A2b 149 CCTCATCTCTACAAACATTTTTTAAAAATATGCCAAGCAT TGTGGCGCAT
AluJo 108 CCCCGTCTCTACAAAAAATA C--AAAAATT AGCCGGGCGTGGTGGCGCGC
A2 197 GCCTGTAGTCCCAGCTATTCAGGAGGCTGAGGTGGGAGGATCACCTGTGC
A2b 199 GCCTGTAGTCCTGGCTATTCAGGAGGCTGAGGTGGGAGGATCACCTGTGC
AluJo 156 GCCTGTAGTCCCAGCTACTC GGGAGGCTGAGGCAGGAGGATCGCTTGAGC
A2 247 CCGGGAGTTCAAGGCTGCAGTGAGCTATGATCACACCACAGTGCTCCAGC
A2b 249 CCAGGAGTTCAAGGCTGCAGTGAGCTATGATCACACCACA ATGCTCCAGC
AluJo 206 CCAGGAGTTC GAGGCTGCAGTGAGCTATGATCGCGCCACT GCACTCCAGC
A2 297 CTGGGCAACAAAGCAAGACTCCATCTCTaaaaataaaata aaattaaaaa
A2b 299 CTGGGCAACAAAGCAAGACTCCATCTCTaaaaataaaatt aaattaaaaa
AluJo 256 CTGGGCGACA GAGCGAGACC CTGTCTCA-- ---------- ----------
A2 347 aaaagatcttcgctgtaaaagaggtacgctcaaatgcaataaaagcatat
A2b 349 aaaagatcttcgatgtaaaagaggtatgctcaaatgcaataaaatcatat
AluJo 284 ---------- ---------- ---------- ---------- ----------
A2 397 aagaaggccgggtgtggtggctcatgcctgtaatcccagcactttgggag
A2b 399 aagaaggccgggtgtggtggctcatgcctgtaatcccagcactttgggag
AluJo 284 ---------- ---------- ---------- ---------- ----------
A2 447 gccg
A2b 449 gctg
AluJo 284 ----
