Shuffling of Genes Within Low-Copy Repeats on 22q11 (LCR22) by Alu-Mediated Recombination Events During Evolution
A1 1 -taaggcagcaggtctgtccaatgttgtgtaaaccaaccaggcctataag
A1b 1 ttaaggcagcaggtctgtccaatgttgtgtaaaccaaccaggcctataag
AluSq 1 ---------- ---------- ---------- ---------- ----------
A1 50 gggaagagaaaaaaatgctgagggcaaggcctagggtaaagaagttgaca
A1b 51 gggaagagaaaaaaatgctgagggcaaggccta-ggtaaagaagttgaca
AluSq 1 ---------- ---------- ---------- ---------- ----------
A1 100 aGGCTGGGCATGGTGGCTCA TGCCTGTAATTCCAGTACTTTGGGAGGCCG
A1b 100 aGGCTGGGCATGGTGGCTCACGCCTGCAATTCCAGTACTTTGGGAGGCCG
AluSq 1 -GGCCGGGCG CGGTGGCTCACGCCTGTAAT CCCAGCACTTTGGGAGGCCG
A1 150 AGGTGGGCGGATCACCTGAGGTCGGGAGTTCGAGACCAGCCTGGCCAACA
A1b 150 AGGTGGGCGGATCACCTGAGGTCGGGAGTTCGAGACCAGCCTGGCCAACA
AluSq 50 AGGCGGGTGGATCACCTGAGGTCAGGAGTTCGAGACCAGCCTGGCCAACA
A1 200 TGGTAAAACC ATGTCTCTACAAAAAAAATCCAAAAATCAGCCGGGTGCGG
A1b 200 TGGTAAAACG -TGTCTCTACAA-AAAAATCCAAAAATCAGCCGGGTGCGG
AluSq 100 TGGTGAAACC CCGTCTCTAC T--AAAAATA CAAAAATTAGCCGGGCGTGG
A1 250 TGGCTCACGCCTGTAATCCCAGTACTTTGGGAGGCCGAGGCGGGCAGATC
A1b 248 TGGCTCACGCCTGTAATCCCAGCACTTTGGGAGGCCAAGGCAGGTGGATC
AluSq 148 TGGCGGGCGCCTGTAATCCCAGCTACTCGGGAGGCTGAGGCAGGAGAATC
A1 300 AC--GAGGTC AGGAGATCGAGA-------- ---------- ----------
A1b 298 ACCTGAGGTCGGGAGTTCGAGA-------- ---------- ----------
AluSq 198 GCTTGAACCCGGGAGGCGGAGGTTGCAGTG AGCCGAGATC GCGCCACTGC
A1 320 ---CCATCCTGGCTAACACGGT-GAAACCCCGTCTCTactaaaaatgcaa
A1b 320 ---CCAGCCTGATCAACATGGT-GAAACCCCGTCTCTactaaaaaatac-
AluSq 248 ACTCCAGCCTGGGCAACAAG AGCGAAACTCCGTCTCA--- ----------
A1 366 aaaaaattagccgggcgtgg -
A1b 365 --aaaactagctgggcatgg t
AluSq 285 ---------- ---------- -
