Different Evolutionary Histories in Two Subgenomic Regions of the Major Histocompatibility Complex

(Downloading may take up to 30 seconds. If the slide opens in your browser, select File -> Save As to save it.)

Click on image to view larger version.

Figure 5.
Figure 5.

The alpha block segments can be separated into two main groups. The phylogenetic relationships of segments a–n were examined by analyzing the multicopy gene families of 1AD3 (A), HCGIV (B), HCGII (C), HERV-16 (D), and HLA class I (E). A scale bar for the number of substitutions per site is included for each tree and the bootstrap percentage from 1000 replications is given for each node. All trees except the HLA class I tree are unrooted. In the HLA class I tree (E), mouse H2 sequences were used as an outgroup and segments corresponding to HLA class I loci are indicated by brackets.

This Article

  1. Genome Res. 9: 541-549

Preprint Server