Loss of Heterozygosity Analysis Using Whole Genome Amplification, Cell Sorting, and Fluorescence-Based PCR

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Figure 5.
Figure 5.

LOH at multiple sites in esophageal adenocarcinoma. Chromosome 9 STRs are labeled from 1 to 5 and alleles are identified asA or B. Electropherograms are representative of the four replicates done for this normal: aneuploid pair. Unambiguous LOH occurs at each locus except 4 (D9S301), where both alleles are retained. (x-axis) Allele size in base pairs; (y-axis) peak height in fluorescent units.

This Article

  1. Genome Res. 9: 482-491

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