Figure 3.
Alignment of Fugu and C. elegans PPEF,Drosophila RdgC, mouse PPEF-2, and human PPEF-1 and PPEF-2 proteins. The alignment was performed with the GCG programs PILEUP and PRETTY. Amino acids at least identical in two aligned sequences are shown in uppercase letters. Residues identical in Fugu and human PPEF-1 and in all proteins, respectively, are shaded. (▾) Identical intron/exon boundaries of Fugu PPEF-1 and humanPPEF-1; (▿) Position of the putative additional splice site in Fugu. Fugu exons 10–11 are numbered. The catalytic domain and the EF hand motif of the PPEF proteins are boxed. The two positions of the Ca2+ chelating side chains are labeled X–Z.
