Panning for Genes—A Visual Strategy for Identifying Novel Gene Orthologs and Paralogs

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Figure 7.
Figure 7.

Mammalian class-mu glutathione transferase paralogs and orthologs. An evolutionary tree of the mammalian class-mu glutathione transferases is shown. The indicated protein sequences were aligned and the alignments used to direct an alignment of the encoding cDNA open reading frames. These DNA sequences were then used to construct evolutionary trees using the PHYLIP DNAML program. Horizontal brackets indicate the three clear ortholog pairs in the tree.

This Article

  1. Genome Res. 9: 373-382

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