Genetic Plasticity of V Genes Under Somatic Hypermutation: Statistical Analyses Using a New Resampling-Based Methodology

Table 3.

Quantiles of FR and CDR Mutability and CDR/FR Mutability Ratio of the Real Sequence Sets Compared to Translationally Equivalent Variants in Various Species

Species Serine included Serine excluded
μ F μ C μ C /μ F μ F μ C μ C /μ F
HumanVH 0.006 0.957 0.998 0.002 0.57 0.744
SheepVλ 0.001 0.976 1 0.001 0.14 0.687
Rainbow troutVH 0.1 0.983 0.994 0.007 0.325 0.805
Horned SharkVH 0.047 0.675 0.974 0.022 0.787 0.983
African toadVH 0.423 0.991 0.985 0.499 0.561 0.546

This Article

  1. Genome Res. 9: 1294-1304

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