Genetic Plasticity of V Genes Under Somatic Hypermutation: Statistical Analyses Using a New Resampling-Based Methodology

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Figure 1.
Figure 1.

Contour plot of the predicted average FR vs. CDR mutability of VH 6-1 variants: (A) 105sequences identical nucleotide composition (black), 105sequences with similar codon composition (blue); (B) 105 sequences with identical amino acid translation (black). The contour levels are drawn at 1, 10, and 100 sequences. The actual gene is shown in red.

This Article

  1. Genome Res. 9: 1294-1304

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