A Prokaryotic Gene Cluster Involved in Synthesis of Lysine through the Amino Adipate Pathway: A Key to the Evolution of Amino Acid Biosynthesis

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Figure 5.
Figure 5.

Comparison of arginine biosynthesis and Thermus lysine biosynthesis related proteins. (A) Phylogenetic relationships among the amino acid sequence encoded in the argC gene ofT. thermophilus and the related sequences. A total of 267 amino acid sites were considered without gap regions in alignment. The bar indicates 10% difference of amino acid sequence. The DAD accession nos. used in this phylogenetic analysis are D64004-19-1, U48355-1-1,X52834-1-1, X99978-2-1, AL031541-2-1, M83659-1-1, Z85982-15-1,AF049897-1-1, M21446-1-1, AE000861-7-1, U67552-4-1, AE000961-28-1,AE000761-6-1, Y10525-2-1, AP000007-35-1, Z69727-9-1, X98880-1-1,U18813-19-1, and L27746-1-1. (B) Phylogenetic relationships among the amino acid sequence encoded in the argB gene ofT. thermophilus and the related sequences. A total of 157 amino acid sites were considered without gap regions in alignment. The DAD accession nos. used in this phylogenetic analysis areAE001016-12-1, AE000806-5-1, U67464-11-1, AE000771-3-1, M94625-2-1,D90905-74-1, X86157-3-1, L06036-3-1, Z26919-3-1, X98880-1-1,U18813-19-1, L27746-1-1, Z69727-9-1, and AP000007-33-1.

This Article

  1. Genome Res. 9: 1175-1183

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