A Comprehensive Approach to Clustering of Expressed Human Gene Sequence: The Sequence Tag Alignment and Consensus Knowledge Base

Table 1.

Tissue Divisions Used for STACK

dbEST 101598 Homo sapiens tissue partitioning
Arbitrary tissue partitions Substituent tissues types Total ESTs
Adipose brown, white 2,376
Brain frontal lobe, cerebrum, cerebellum, cortex 177,719
Cochlea fetal cochlea 4,304
Connective bone, skin, synovial membrane 40,753
Digestive stomach, colon, gall bladder 51,032
Disease duplicates of ESTs annotated as tumors 114,496
Eye retina, cornea, ocular 28,514
Genomic specified chromosomes 101,986
Glands breat, endocrine 112,346
Heart fetal heart, aorta 69,830
Hemato-lymphatic blood, kidney, liver–spleen 255,565
Lung trachea, larynx, lung 70,259
Muscle leg, pectoral 16,237
Olfactory olfactory epithelium 2,600
Other monocytes, mononuclear cells 25,925
Reproductive ovary, testis, uterus 239,161
  • Sequences were partitioned over an arbitrarily defined tissue hierarchy designed to group physically related tissues and remain within constraints of computational resources. Genomic tissue is a set of ESTs labeled only as having a genomic region of hybridization without a tissue source. The set of duplicate copies of all disease-related sequences is loosely referred to as a tissue for this work.

This Article

  1. Genome Res. 9: 1143-1155

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