Amino acid sequences of putative Cer7 Env protein (A) and accessory protein C (B). (A) The leader sequence and transmembrane domain of Env are bracketed beneath and labeled. The predicted signal peptide cleavage site is indicated by a vertical arrowhead. The seven N-glycosylation targets “NXT/S” are boxed. The grey box indicates a putative furin cleavage site. Vertical double headed arrows at left of the sequence delineate the leader (L), surface (SU), and transmembrane (TM) domains of Env. (B) Gray boxes indicate the two predicted coiled-coil regions of ORF C. The mulitple cysteine and histidine residues are shown in bold and underlined. See Methods for a description of the functional motif predictions.
