Extreme Reduction of Chromosome-Specific α-Satellite Array Is Unusually Common in Human Chromosome 21

(Downloading may take up to 30 seconds. If the slide opens in your browser, select File -> Save As to save it.)

Click on image to view larger version.

Figure 7.
Figure 7.

Relative frequency distribution curves of interphase FISH using the probe αRI performed on a cohort of 73 DS cell lines (◼). (○) The results derived from Fig. 1 of the control group using the same probe. Horizontal axis represents the percentage of cells in each cell line showing the expected five interphase FISH signals for DS cells. Data points represent the mid-values of the bins (in the range of 10%) used for the construction of the frequency distribution diagram. Vertical axis denotes the number of cell lines in each bin expressed as a fraction of the total number of cell lines investigated.

This Article

  1. Genome Res. 9: 895-908

Preprint Server