Extreme Reduction of Chromosome-Specific α-Satellite Array Is Unusually Common in Human Chromosome 21

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Figure 6.
Figure 6.

Q-FISH analysis of the centromeric αRI domain and the 876D4 genomic region at 21q22.1–22.2 in a cell line containing one low-alphoid chromosome 21. Each point represents the fluorescence intensities of αRI and 876D4 probe on a particular chromosome; (○) a normal-alphoid chromosome 21; (◼) a low-αRI chromosome 21. Each data set shows a good fit to a straight line by linear regression. (a.f.u.) Arbitrary fluorescence units.

This Article

  1. Genome Res. 9: 895-908

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