Genomics and Hearing Impairment

Table 1.

Expected Test Results for a Selection of Putative Locations of Common Hearing Deficits

Test results Middle ear Outer hair cells Inner hair cells Auditory nerve Brainstem
Air conduction Ab Ab Ab ambig N
 pure tone
 audiogram
Bone N Ab Ab ambig N
 conduction
 pure tone
 audiogram
Tympanometry Ab N N N N
Middle ear Ab N ambig Ab Ab
 muscle
 reflexes
Otoacoustic Ab Ab ambig N N
 emissions
Auditory N N Ab Ab Ab
 brainstem
 response
  • (Ab) Absent or abnormal; (N) normal or generally unaffected in morphology if residual peripheral hearing is adequate; (ambig) ranges from normal to abnormal and thus does not contribute diagnostic information.

This Article

  1. Genome Res. 9: 7-16

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