
Nonrecombinant region for positional cloning of mnd2. The distance between the closest recombinant markers, D6Mit164 andD6Mit211, is ∼400 kb (Weber et al. 1998). Mouse BAC 245c12 was sequenced by the random shotgun method to generate contigs of 42, 12, and 108 kb. The genes D6Mm5e, Dok, andLor2 were identified in the 108 kb contig as described in the text (not shown to scale). Human BAC clone 173E10 was isolated by hybridization with a mouse D6Mm5e cDNA.











