Table 1.
Summary of FISH Data
| Probe | Positions covered | Patient RB | Patient MC |
| Initial screen | |||
| y133B06 | 101–103 | ++ | ++ |
| y934D03 | 111–118 | +− | ++ |
| y951C04 | 120–124 | +− | ++ |
| y918D08 | 140–141 | +− | +− |
| Secondary screens | |||
| y939H03 | 106–109 | ++ | N.D. |
| dJ213-J23 | 108 | ++ | N.D. |
| dJ104-A7 | 109 | ++ | N.D. |
| dJ101-N13 | — | ++ | N.D. |
| dJ261-O4 | — | +− | N.D. |
| dJ9-D18 | 111 | +− | N.D. |
| y975F11 | 127–134 | N.D. | ++ |
| dJ177-H4 | 135 | N.D. | +− |
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Metaphase spreads from patients RB and MC were initially screened by FISH with a set of four YACs to give an approximate breakpoint location. This was followed by FISH experiments with YAC and PAC probes to give a higher resolution localization. YAC clones are prefixed by y; PAC clones by dJ.
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↵The positions ordered in the YAC contig of Fig. 1 plus a location of each probe within it.
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↵(++) Hybridization to both normal and deleted chromosomes; (+−) hybridization to normal chromosome only. (N.D.) Experiment not done.
