Figure 4.
Residues at conserved positions within box VI and VII that make known or potential interactions with an ATP bound to an adjacent subunit. (a) Empirically determined contact within NSF–D2 between Lys-631 and an ATP phosphate group. (b) Hypothetical interaction between Glu-133 and Arg-158 of Pol III δ′ and an adjacent ATP magnesium ion and phosphate group. (See text for residue positions in the alignment.) Color scheme: Residue positions are shaded red proportional to the degree of sequence conservation in the alignment, residue side chains for highly conserved positions are orange, ATP is cyan, and magnesium is green.
