A Computer Program for Aligning a cDNA Sequence with a Genomic DNA Sequence

Table 2.

Accuracy of sim4 with Simulated ESTs

Rate (%) 1 2 3
1 0.15 0.23 89.5
3 0.20 0.35 81.7
5 0.26 0.47 75.7
  • The numbered columns record the following data. (1) The percentage of nucleotides in putative sim4 exons that are not in the true mRNA. For instance, at a rate of 1% simulated errors, each 500-bp simulated EST had an average of five errors. The 0.15% false-positive rate means that an average of 500 × 0.0015 = 0.75 predicted nucleotides were not in the true mRNA. (2) The percentage of nucleotides in the true mRNA but not in putative sim4 exons. (3) The percentage of splice junctions that were determined exactly.

This Article

  1. Genome Res. 8: 967-974

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