Duplication of a Genomic Region Containing the Cdc2L1-2 and MMP21-22 Genes on Human Chromosome 1p36.3 and their Linkage to D1Z2

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Figure 2.
Figure 2.

Detailed schematic comparing the relationship between the structure of the PITSLRE protein kinase and Cdc2L1/Cdc2L2. The structure of the PITSLRE protein kinase and the Cdc2L exons that encode the protein is shown in detail at top. Amino acid differences between the proteins encoded by Cdc2L1 and Cdc2L2 are indicated below the protein schematic. Directly below this schematic are representations of the various PITSLRE mRNAs (denoted as splice variants) generated by alternative splicing from Cdc2L1,Cdc2L2, or both.

This Article

  1. Genome Res. 8: 929-939

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