Genome Scan and Congenic Strains for Blood Pressure QTL Using Dahl Salt-Sensitive Rats

Table 5.

Systolic Blood Pressure and Heart Weight by Genotype at D7Mit5 for the F2(S × LEW) Population Raised on an 8% NaCl Diet

Genotype One-way ANOVA (P)
SS SL LL
Blood pressure (mmHg) 178.7 ± 4.30 186.9 ± 4.30 196.8 ± 5.66 0.052
Heart weight (mg) 1143 ± 19 1212 ± 20 1290 ± 28 0.0002
Heart weight, BP adjusted (mg) 1178 ± 13 1218 ± 13 1252 ± 20 0.010
Body weight (grams) 348 ± 4.0 353 ± 3.1 354 ± 4.4 0.49
  • Means ± s.e. are given; data are for all 151 rats. Differences were analyzed by a one-way ANOVA. (S) S rat allele; (L) LEW allele.

  • Heart weight adjusted by regression analysis for differences in blood pressure.

This Article

  1. Genome Res. 8: 711-723

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