Chicken Microchromosomes Are Hyperacetylated, Early Replicating, and Gene Rich

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Figure 1.Figure 1.
Figure 1.

Acetylated histone H4 and CGIs are concentrated on MICs. (a) CGI–FISH. (i) DAPI-stained DT40 chromosomes. (ii) CGI library probe (green) prepared and used as in McQueen et al. (1996), showing strong signal in MICs. (iii) CGI library probe without counterstain showing the contrast in signal intensity between the MIC and MAC groups. (b) H4 acetylation immunolabeling. (i) DAPI-stained DT40 chromosomes. (ii) H4 acetylation immunostaining (green) showing strong staining over MIC clusters. (iii) H4 acetylation immunostaining without counterstain showing the contrast in signal intensity between the MIC and MAC groups.

This Article

  1. Genome Res. 8: 621-630

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