Table 4.
Rates of Nonsynonymous and Synonymous Substitution of Three Distinct Ribonucleases of the RNase A Gene Superfamily
| Coding sequence | K a vs. 2T | r 2 | K svs. 2T | r 2 |
| RNase k6 | 0.40 | 0.81 | 1.1 | 0.54 |
| EDN (RNase 2) | 1.9 | 0.98 | 2.9 | 0.80 |
| ECP (RNase 3) | 2.0 | 0.92 | 1.7 | 0.97 |
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The rates of ns/ns/yr (K a vs. 2T) and synonymous substitution/synonymous site/year (K svs. 2T) for RNase k6 were calculated as described (Li 1993), with years of divergent evolution (2T) from Sibley and Ahlquist (1984). Values forK a and K s for EDN (RNase 2) and ECP (RNase 3) were taken from Rosenberg et al. (1995).











