Sequences diagnostic of the new subfamily. Diagnostic sequences were determined from alignments of all inferred protein sequences from ESTs, complete cDNAs, and genomic sequences of subfamily members from S. cereviseae, C. elegans, and mammals, as well as fromSchizosaccharomyces pombe, Plasmodium falciparum, andDrosophila melanogaster (see footnote in Discussion). Numbered sequences are P-type ATPase consensus sequences; lettered sequences are other diagnostic sequences. Numbers in parenthesis are the number of different gene sequences used to determine the diagnostic sequences; total numbers vary because incomplete sequences may not overlap all diagnostic regions.
