EbEST: An Automated Tool Using Expressed Sequence Tags to Delineate Gene Structure

Table 1.

Exon Prediction Evaluated at the Exonic Level, Using the 176 ALLSEQ Human Genes as Test Case

  Unmutated Mutated
Sn Sp ME WE Sn Sp ME WE
FGENEH 0.71 0.68 0.11 0.15 0.31 0.34 0.28 0.20
GeneID+ 0.69 0.65 0.09 0.18 0.27 0.26 0.27 0.30
GeneParser 3 0.61 0.61 0.11 0.14 0.34 0.41 0.28 0.11
Grail 2 0.49 0.53 0.19 0.13 0.24 0.27 0.32 0.13
EbEST 0.37 0.58 0.43 0.02 0.31 0.53 0.43 0.08

  • ↵(Sn) Sensitivity; (Sp) specificity. The data for FGENEH, GeneID+, GeneParser 3, and Grail 2 were cited and recalculated from Burset and Guigo (1996). (For details, see Methods.)

This Article

  1. Genome Res. 8: 268-275

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