Allele Frequency Distributions in Pooled DNA Samples: Applications to Mapping Complex Disease Genes

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Figure 6.
Figure 6.

The relationship between pooled and direct allele frequencies. They-axis shows the allele frequency estimate from a DNA pool, and the x-axis that from direct genotyping. The data are 131 alleles from all T and U chromosomes compared at the tetranucleotide markers in the Mennonites. The solid and the broken lines show the fitted linear regression and the line expected from perfect agreement, respectively.

This Article

  1. Genome Res. 8: 111-123

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