Allele Frequency Distributions in Pooled DNA Samples: Applications to Mapping Complex Disease Genes

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Figure 3.
Figure 3.

RH map of segment 13q22–13q31 on human chromosome 13. The map shows the location of all chromosome 13q markers used in DNA pooling for localizing a HSCR susceptibility gene. All uniquely placed markers are supported with odds of at least 100:1, except for D13S792 (supported with 20:1 odds); D13S921 maps to the interval between D13S170 and D13S790. The HSCR gene EDNRB is located within 1.4 Mb of D13S317 as determined from YAC physical mapping (Puffenberger et al. 1994b). In this chromosome 13 RH panel, 1 cR9000 is ∼70 kb of DNA (Shaw et al. 1995).

This Article

  1. Genome Res. 8: 111-123

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