Figure 4.
Chip image comparisons for a heterozygous nucleotide substitution. (a) False colored image of GMO8388 target hybridization to anATM sense array (1.2 × 1.2 cm) is given. Probes with greatest hybridization signal are given in white and red; those of lowest signal are given in blue and black. A magnified view of the probe sets (50 μm feature size) interrogating nucleotide position 5932 in samples GM11261 (5932 G/G) and GMO8388 (5932 G/T) is shown inb and c, respectively. The identity of the interrogated ATM cDNA nucleotide positions 5922–5942 is given with IUPAC ambiguity codes and position 5932 is underlined.
