Quality Assessment of Whole Genome Mapping Data in the Refined Familial Spastic Paraplegia Interval on Chromosome 14q

Table 2.

Comparison of EST Localization between RH Genebridge 4 Panel and YAC Contig

ESTs mapped with RH Genebridge 4 panel
Δlog10L = 0 0 < Δlog10L < 1 1 < Δlog10L < 2 2 < Δlog10L < 3
A. Interval (D14S259; D14S978)
Assigned ESTs  (RH) 30 3 8 14
Concordant  mapping  (RH/YAC contig) 16 2 4 2
Discordant  mapping (RH/YAC contig) 14 0 0 1
RH mapping vs  YAC contig  undetermined 0 1 4 11
B. Interval (D14S978; D14S276)
Assigned ESTs  (RH) 26 22 3 7
Concordant  mapping (RH/YAC contig) 20 1 2 0
Discordant  mapping  (RH/YAC contig) 0 12 0 0
RH mapping vs  YAC contig  undetermined 6 9 1 7
  • Δlog10L = log10. Likelihood difference from the best location.

  • The position found on the YAC contig is identical to the most likely position obtained on the RH map.

This Article

  1. Genome Res. 8: 1216-1227

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