

YAC contig map of the SPG3 region. The 90 STSs, including polymorphic markers and ESTs for which GenBank accession numbers are indicated in italics, are listed along the second line at top. The two thick black lines surrounding loci D14S259 and D14S1018 represent the proximal and distal borders of the SPG3 interval, respectively. Polymorphic markers appearing on the last version of Généthon genetic map are framed with a thicker line. Each of the 32 YAC clones is depicted by dark grey rectangles with its name given to the left and to the right. Presence or absence of an STS in the corresponding YAC clone is indicated by dark or light grey squares. RH mapping data using the TNG panel are presented at top: The 22 linkage groups defined by a pairwise lod score above 4 are indicated on the first line, a 0 is used to describe STSs that did not amplify on TNG, and the colors along the second line correspond to the 11 linkage groups containing more than one STS. Positions of ESTs H68092 and H99050, which generate an internal deletion in YAC 965B6, were those defined by TNG RH mapping data.











