WebWise: Web Sites of the Human Genome Project

  1. Kim D. Pruitt1
  1. National Center for Biotechnology Information, National Library of Medicine, National Institutes of Health, Bethesda, Maryland 20894 USA

This extract was created in the absence of an abstract.

In this last decade of the twentieth century the scientific community has witnessed the progression of a historic project—The Human Genome Project (HGP)—and a corresponding escalation in the rate of DNA sequence data accumulation. Managing, understanding, tracking, and storing this volume of data are not trivial tasks. The public data repositories have expanded their resources to receive, store, and retrieve sequence and map data. Furthermore, recognizing that the full extent of the data (including project descriptions and protocols) should be organized and publicly accessible, the HGP sequencing centers provide their own web sites. These sites allow for rapid dissemination of a wealth of data and information, including map and sequence data, protocols, software tools, and overviews of goals and progress. As such, it is useful to have an understanding of the general organization and content of these web sites.

The HGP Web Sites

Over the past year, this WebWise series has reviewed a dozen web sites hosted by the larger HGP sequencing centers. These sites and the URLs to their Home pages are listed, in order of review date, in Table1. Each review provided an indication of the contents and main features, as well as an organizational diagram, of the center’s web site. As web sites are often subject to revision, these sites were revisited for this final review to determine whether any large changes have been made since the original review.

View this table:
Table 1.

HGP Sequencing Center Web Sites Included in the WebWise Series

Naturally, there has been an increase in the quantity of data available, and several centers have expanded the overall long-term goals for their center. Table 2 provides an indication of the centers that are currently engaged in sequencing each chromosome. Please note that the table only includes the reviewed groups, but there are additional HGP sequencing centers. Only three centers …

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