
Hypothetical pathway for evolution of a dynamic archaeal replicon, pNRC100, in Halobacterium sp. strain NRC-1. The processes involved include IS element-mediated replicon fusions and transposition, and homologous recombination-mediated gene conversion and inversion. This model is based on the complete sequence analysis of the 191,346 bp replicon. Cover design by Michele Savelle. (For details see Ng et al., p. 1131.)