Table 4.
Phylogenetically Restricted Sequences of the Apicomplexa
| Reference (dbEST ID no.) | Contig ID (no. of ESTs) | P value for apicomplexan genera | P value of closest nonapicomplexan | Putative identification | dbEST/ GenBank accession nos. |
| Apical antigens/adhesins | |||||
| 467174 | TQ-753 (92) | Neospora(10−22) | 100 | dense granule antigen | U72991 |
| 467174 | Plasmodium (10−3) | Pf-EMP1 | U27338 | ||
| 467347 | Sarcocystis(10−15) | 10−1 | microneme protein | L08892 | |
| 467347 | Eimeria(10−14) | A22655 | |||
| 466328 | TQ-702 (2) | Plasmodium(10−12) | 10−1 | apical membrane antigen I | L27503 |
| 475702 | TQ-1456 (2) | Plasmodium(10−14) | 10−10 | stippled structure-assoc. antigen | U10121 |
| Developmental antigens | |||||
| 466318 | TQ-11 (8) | Eimeria(10−50) | 10−1 | 19-kD sporozoite antigen | M59500 |
| 620297 | Plasmodium(10−13) | 10−7 | gametocyte-specific antigen Pfs97 | Z37724 | |
| 489378 | Plasmodium(10−11) | 10−1 | trophozoite antigen (Ser kinase?) | Z11832 | |
| 487888 | Plasmodium(10−11) | 10−6 | M83793 | ||
| 574122 | TQ-254 (12) | Eimeria(10−31) | 10−10 | developmental mRNA | M98840 |
| 574122 | Plasmodium(10−20) | M29000 | |||
| Metabolism, signaling, structural | |||||
| 513090 | Plasmodium(10−20) | 10−8 | RNA polymerase III (large subunit) | M73770 | |
| 653609 | TQ-1975 (4) | Plasmodium(10−13) | 10−9 | HMG protein | L31630 |
| 653609 | Babesia(10−13) | M81360 | |||
| 574303 | Plasmodium(10−11) | 10−4 | P-type ATPase | U39298 | |
| 574303 | Cryptosporidium(10−10) | U65981 | |||
| 487624 | Eimeria(10−23) | 10−14 | transhydrogenase | L08392 | |
| 467004 | Eimeria(10−15) | 10−6 | |||
| 489375 | Eimeria(10−11) | 10−2 | |||
| 488081 | TQ-1442 (11) | Neospora(10−28) | 10−4 | 14-3-3 regulatory protein | U31542 |
| 465739 | Neospora(10−23) | 10−16 | |||
| 571541 | Neospora(10−67) | 10−33 | |||
| Unknown function | |||||
| 467430 | TQ-627 (9) | Cryptosporidium(10−17) | 10−9 | EST (identity unknown) | AA224687 |
| 465760 | TQ-377 (4) | Plasmodium(10−39) | 10−10 | aspartate-rich protein | U46930 |
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↵Available from the Toxoqual database listing the consensus sequence for aligned EST contigs http:/daphne.humgen.upenn.edu/toxodb/
