Gene Discovery by EST Sequencing in Toxoplasma gondiiReveals Sequences Restricted to the Apicomplexa

Table 3.

Functional Classification of Conserved Protein Domains vs. Yeast Proteins That Are Homologous to Toxoplasma ESTs

Number of matching sequences
P-fams yeast proteins
Protein kinases/phosphatases 2 4
RNA/DNA binding 5 5
Translation/secretion 3 18
Signaling 4 3
Heat shock/chaperones 7 11
Amino acid metabolism 3 7
Detoxification 4 3
Glycolysis/energy metabolism 13 13
Nucleotide binding/ATP synthases 6 6
Proteases 3 3
Proteosome/ubiquitin 3 11
GTPases/ATPases 3 8
Cytoskeleton/cell adhesion/structural 7 8
Ribosomal proteins 25 67
Mitochondrial 5 10
Purine/pyrimidine metabolism 5 4
DNA/RNA replication/transcription 7 20
  • Number of distinct conserved domain family members (P-fam) or yeast proteins recognized by toxoplasma ESTs.

This Article

  1. Genome Res. 8: 18-28

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