Small Open Reading Frames: Beautiful Needles in the Haystack

Table 1.

A Sample of Some Proteins Encoded by smORFS

YPD name CAI Length Encoded Function
AGA2 0.088 88 N A-agglutinin binding subunit
ATP15 0.167 63 M F1–ATP synthase epsilon subunit
ATP8 0.226 48 M F0–ATP synthase subunit 8
COX7 0.204 61 M cytochrome c oxidase subunit VII
COX8 0.224 79 M cytochrome c oxidase subunit VIII
COX9 0.264 60 M cytochrome c oxidase chain VIIA
CRS5 0.233 70 N metallothionein-like protein
CUP1A 0.226 62 N metallothionein, copper chelatin
CUP1B 0.226 62 N metallothionein, copper chelatin
CWP2 0.747 93 N Cell wall mannoprotein
DDR2 0.297 62 N stress protein
HOR7 0.365 60 N hyperosmolarity responsive
INH1 0.130 86 M mitochondrial ATPase inhibitor
MFA1 0.556 37 N Mating pheromone a-factor
MFA2 0.271 39 N Mating pheromone a-factor
OST4 0.461 37 N oligosaccharyltransferase subunit
PMP1 0.672 41 N plasma membrane proteolipid
PMP2 N.D. 44 N plasma membrane proteolipid
RPL47A 0.417 26 N ribosomal protein
RPL47B 0.438 26 N ribosomal protein
SAE3 0.107 51 N meiotic recombination pathway
SCH1 0.188 55 N similar to protein kinase A inhibitor
STF1 0.171 86 M ATPase stabilizing factor
TOM6 0.300 62 M mitochondrial integral outer membrane
TOM7 0.222 61 M subunit of mitochondrial protein translocase
YAR020C 0.482 56 N similar to PAU3
YS29A 0.652 57 N ribosomal protein
YS29B 0.760 57 N ribosomal protein
YSY6 0.160 66 N secretory pathway
ACB1 0.360 88 N acyl-coenzyme A-binding protein
ATP9 N.D. 76 M F0–ATP synthase subunit 9
ATX1 0.169 74 N metal homeostasis and antioxidant

This Article

  1. Genome Res. 7: 768-771

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