Table 1.
Advanced Microbial Genome Projects and Their Status
| Species and taxonomic position | Genome size (Mb) | Status | Presenter (institution) |
| Bacteria | |||
| Escherichia coli(Proteobacteria) | 4.64 | complete; released, submitted to GenBank with preliminary annotation; detailed annotation in progress | Fred Blattner (University of Wisconsin, Madison) |
| Helicobacter pylori(Proteobacteria) | 1.67 | complete; annotation in progress | Jean-Francois Tomb (TIGR) |
| Treponema pallidum(Spirochaetales) | 1.05 | nearly complete (several gaps remaining) | Claire Fraser (TIGR) |
| Borrelia burgdorferi(Spirochaetales) | 1.3 | in progress, completion expected in 1997 | Claire Fraser (TIGR) |
| Ureaplasma urealyticum(Gram-positive bacteria, Mycoplasmas) | 0.76 | nearly complete | Elliot J. Lefkowitz (University of Alabama, Birmingham) |
| Streptococcus pneumoniae (low G+C Gram-positive bacteria) | 2.05 | nearly complete (several gaps remaining) | Brian A. Dougherty, TIGR |
| Neisseria gonorrhoeae (Proteobacteria) | 2.05 | >95% complete; contig sequences available through WWW | Bruce A. Roe (University of Oklahoma, Oklahoma City) |
| Streptococcus pyogenes (low G+C Gram-positive bacteria) | 1.92 | >95% complete; contig sequences available through WWW | Bruce A. Roe |
| Mycobacterium tuberculosis (Gram-positive bacteria, Actinomycetes) | 4.4 | >75% complete | Robert D. Fleischmann (TIGR); Bart Barrell (The Sanger Center, Hinxton, Cambridge, UK) |
| Rickettsia prowazekii(Proteobacteria) | 1.1 | >80% complete; detailed analysis in progress | Siv G.E. Andersson (Uppsala University, Sweden) |
| Aquifex aeolicus (oxygen-reducing bacteria) | 1.55 | nearly complete (2 short gaps remaining) | Ronald V. Swanson (Recombinant Biocatalysis Inc., Sharon Hill, PA) |
| Archaea | |||
| Methanobacterium thermoautotrophicum (Euryarchaeaota, Methanobacteriales) | 1.7 | complete; annotation in progress | Douglas R. Smith (Genome Therapeutics Corporation, Waltham, MA) |
| Archaeoglobus fulvidus (Euryarchaeaota, Archaeaoglobales) | 2.2 | nearly complete (one short gap remaining); annotation in progress | Hans-Peter Klenk (TIGR) |
| Pyrobaculum aerophilum (Crenarchaeota, Thermoproteales) | 2.2 | nearly complete; annotation in progress | Sorel Fitz-Gibbon (University of California, Los Angeles) |
| Pyrococcus furiosus(Euryarchaeaota, Thermococcales) | 2.1 | in progress; complete genomes covered by clones | Robert B. Weiss (University of Utah, Salt Lake City) |
| Sulfolobus solfataricus (Crenarchaeota, Sulfolobales) | 3 | >50% sequenced; completion expected by the end of 1997 | Christoph W. Sensen (Institute for Marine Biosciences, National Research Council of Canada, Halifax, Nova Scotia) |
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↵Complete genomes released and published prior to the meeting are not included. Genome projects that are only in their early stages are not mentioned either.
