Single-Nucleotide Polymorphism Identification Assays Using a Thermostable DNA Polymerase and Delayed Extraction MALDI-TOF Mass Spectrometry

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Figure 4.
Figure 4.

Specificity of primer extension reaction in the presence of 4 ddNTPs. The lacI model system was tested in the presence of ThermoSequenase, all four ddNTPs, and targets containing a different base at the polymorphic site. (A) G target; (B) A target; (C) T Target; (D) C target; (E) negative enzyme control.

This Article

  1. Genome Res. 7: 378-388

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