Large-Scale Comparative Sequence Analysis of the Human and Murine Bruton’s Tyrosine Kinase Loci Reveals Conserved Regulatory Domains

Table 2.

Summary of Sequence Conservation in the BTK Region

Total human sequence conserved (bp) Percent of total sequence in the region or locus
Coding and noncoding sequence
 entire region 18,634 24.5
 BTK locus 9,905 27.0
Noncoding Sequence
 entire region 11,193 16.3
 BTK locus 7,405 21.7
 GLA locus 1,089 12.4
 L44L locus 133 5.4
 FCI-12 locus 306 16.3
Average percent conservation of coding sequence 87.0 Average percent conservation of noncoding sequence 72.7
  • As aligned by SIM and extracted with CONSERVED.

This Article

  1. Genome Res. 7: 315-329

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