Large-Scale Comparative Sequence Analysis of the Human and Murine Bruton’s Tyrosine Kinase Loci Reveals Conserved Regulatory Domains

Table 1.

Gene Comparisons

Gene Length (bp/aa) Percent identity Percent similarity
human mouse
FTP-3 cDNA 2197/ 2150/ 91.7
protein 449 449 99.1 99.1
GLA cDNA 1349/ 1378/ 82.2
protein 429 419 78.0 86.9
L44L cDNA 408/ 392/ 91.2
protein 106 106 100 100
BTK cDNA 2560/ 2468/ 87.8
protein 659 659 98.3 99.4
FCI-12 cDNA 1000/ 832/ 81.3
protein 97 97 94.9 97.9

  • ↵Both the 5′ and 3′ untranslated regions (UTR) are included in cDNA comparisons. (aa) Amino acids.

  • ↵Similarity accounts for conservative physical property changes in the amino acids.

This Article

  1. Genome Res. 7: 315-329

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