Long Human–Mouse Sequence Alignments Reveal Novel Regulatory Elements: A Reason to Sequence the Mouse Genome

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Figure 3.
Figure 3.

Alignments of the mouse XRCC1 region and a mouse EST (the reverse complement of GenBank accession no. W14361). Aligning regions 7748–7864 and 8741–8765 of the mouse sequence (accession no. L34078) correspond to positions 280–396 and 397–421 of the EST and to positions 1020–1136 and 2465–2489 of human (accession no. L34079). The alignment terminates at the end of the EST, and consensus splice junctions (intron = CT...AC), conserved between human and mouse, indicate a gene transcribed from right to left.

This Article

  1. Genome Res. 7: 959-966

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