Figure 1.
Predicted amino acid sequence of hRPC155. The conserveda–h regions are underlined. The consensus Zn2+ binding domain in the a region is indicated in bold letters. The locations of the similarity to the helix J–turn–helix K motif present in E. coli DNA polymerase I and T7 DNA polymerase, and of the Mg2+ binding site, are indicated. The boxed amino acids at the carboxyl terminus of hRPC155 correspond to the synthetic peptide CSH-499 that was used to raise the anti-hRPC155 antibody (antibody α-CSH499, rabbit CS377).
