Transcription and potential functions of a novel XIST isoform in male peripheral glia

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Figure 3.
Figure 3.

Assessment of ATAC-, RNA-, and ChIP-seq read coverages over the XIST locus. (A) snRNA/ATAC-seq tracks from CATlas heart data set. (B) RNA-seq (±strands) and H3K4me3, H3K4me1, H3K27ac, and H3K36me3 ChIP-seq from two human male tibial nerve samples and ATAC-seq tracks from one human male and two female sciatic nerve samples in the ENCODE database. (C) snATAC-seq tracks from CATlas multitissue data set. (AC) All plots show the region at Chr X: 73,790,905–73,854,216 from the hg38 reference genome. The 3′ region of XIST exon 1 is enclosed by two red dashed lines. TSIX gene location spanning Chr X: 73,792,205–73,829,231 on the + strand is shown as a blue bar, indicating the RNA-seq reads were from XIST but not TSIX. For each track, cell types and/or sequencing modality are shown on the left, and the data range is shown in the right. Additional data for the tibial and sciatic nerve samples are in Supplemental Figure S7.

This Article

  1. Genome Res. 36: 257-274

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