Mitotic chromosomes harbor cell type– and species-specific structural features within a universal loop array conformation

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Figure 2.
Figure 2.

Hi-C data show compartments and TADs are lost in both mitotic mESCs and C2C12. (A,B) Hi-C heat map of Chr 11 at 100-kb bins for mESCs (A) and C2C12 (B) nonsynchronized cells (left panel) and mitotic arrested and sorted cells (right panel). (C,D) Zoom-in Hi-C heat map of Chr 11: 43,000,000–47,000,000 at 25-kb bins for mESC (C) and C2C12 (D) for nonsynchronized cells (left panel) and mitotic arrested and sorted cells (right panel).

This Article

  1. Published in Advance June 6, 2025, doi: 10.1101/gr.280648.125 Genome Res. 35: 1733-1744

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