Table 1.
Studies investigating the origin of ORFans in bacteria
| Year of publication | Hypotheses investigated | Taxa investigated | Reference |
|---|---|---|---|
| 2024 | Emergence from noncoding sequences, frameshifting, phage origin | Various taxa in human gut microbiome | Vakirlis and Kupczok 2024 |
| 2023 | Emergence from noncoding sequences | Bacillus genus | Karlowski et al. 2023 |
| 2021 | Frameshifting | Escherichia coli | Watson et al. 2021 |
| 2015 | Phage origin | Various | Lobb et al. 2015 |
| 2010 | Emergence from intergenic sequences, frameshifting, phage origin | Various | Yomtovian et al. 2010 |
| 2009 | Phage origin | Various | Cortez et al. 2009 |
| 2006 | Phage origin | Various | Yin and Fischer 2006 |
| 2004 | Phage origin | Escherichia coli | Daubin and Ochman 2004a |











