De novo gene birth and the conundrum of ORFan genes in bacteria

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Figure 1.
Figure 1.

Workflow for detecting ORFans and de novo–emerged genes. (A) An augmented search strategy for detecting actual and excluding artifactual ORFan genes. (B) The gold standard of de novo gene detection. (Created with BioRender; https://www.biorender.com/.)

This Article

  1. Published in Advance July 10, 2025, doi: 10.1101/gr.280157.124 Genome Res. 35: 1679-1688

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